When summoned, Guile will remain crouched in one place, frequently throwing his Sonic Boom special at enemies. When an opponent gets close he will immediately perform his Somersault Flash Kick. This odd habit seems to be in reference to a common playstyle that Guile players use throughout the series.
Guile is a Captain of the US Air Force and is frequently hunting down the evil Shadaloo warlord M. Bison in an attempt to avenge the supposed death of his friend Charlie Nash, although as seen in Street Fighter II, his quest for vengeance leads him to abandon his wife Jane and his daughter Amy, though in his arcade ending, they convince him to come back home, telling him that killing Bison won't bring Charlie back, and that it'd make Guile a murderer.
Guile continues to oppose Shadaloo's activities throughout the series and frequently works with Interpol officer Chun-Li.
Guile is stationary for the majority of his stay, firing Sonic Boom from his position, which travels about half of Final Destination. If an opponent gets too close, Guile uses Somersault Flash Kick, which knocks them away vertically. After around 15 seconds, Guile stands up and disappears.
- Guile's other crossover appearances include Marvel vs. Capcom 2, Capcom vs. SNK and Capcom Fighting Evolution.