The Dr. Mario series is a series of puzzle games involving the video game character Dr. Mario.

Main games

Dr. Mario

Dr. Mario is a puzzle game similar to Tetris. In the game, players play as the titular character and use vitamins to destroy three different colored viruses. This game was re-made to the Game Boy Advance as NES Classics: Dr. Mario.

Tetris & Dr. Mario

A remake of the original, packaged along with an updated Tetris. A mode was introduced, where bouts of both games could be played one after the other.

Dr. Mario 64

This was the first game to the series to introduce a story mode, in which Dr. Mario and Wario are playable. It is a remake of the original Dr. Mario.

Dr. Mario Online Rx

Dr. Mario Online Rx is a puzzle video game starring Dr. Mario released on May 26, 2008 in North America and March 25, 2008 in Japan for WiiWare. This game features Miis as playable characters and had Wi-Fi capabilities.

In Super Smash Bros. Melee


The series' main protagonist, Dr. Mario, is a hidden character, serving as a clone of Mario. Dr. Mario's trademark item, the Megavitamin, is used as his Standard Special Move; it is also used in his taunt. Also, one of his theme songs, Fever, is included in the game.

In Super Smash Bros. Brawl

Dr. Mario was removed from Brawl as a playable character, likely due to being a clone. Dr. Mario and the viruses in the games are stickers in the game, and his song used in Super Smash Bros. Melee is used in the PictoChat stage in Brawl, as well as other of these, Chill.

In Super Smash Bros. for Wii U and 3DS

Dr. Mario - Super Smash Bros. for Nintendo 3DS and Wii U

Dr. Mario reappears as a playable veteran in this game.

Nurse Peach is mentioned in the info section of the Wii U version.
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